Episode 47: The Immunopathogenesis of Early Lyme Disease

Mary Petzke, Ph.D.

Cindy Kennedy, FNP, is joined by Mary M. Petzke, Ph.D., who discusses the process of Lyme Disease development and how it relates to your immune system. Petzke is a principal investigator and assistant professor in the Department of Microbiology and Immunology at New York Medical College, Valhalla, N.Y., where she studies the immunopathogenesis of early Lyme disease and educates future physicians.

Petzke earned her doctorate at Brown University, Providence, R.I., and received post-doctoral training at Harvard Medical School before moving to southern New York and discovering Lyme disease in 2005. Petzke’s laboratory employs global gene expression profiling, RNA sequencing and bioinformatics analysis to examine interactions occurring between Borrelia burgdorferi and the innate immune system. She is particularly interested in identifying factors that enable the spirochete to evade defenses in the skin and disseminate to other target tissues. A second line of research focuses on the development of gene expression-based diagnostic tests for active Lyme disease.